Uncovering the Mechanisms of Human Disease

Imagine simulating diabetes, lung cancer, or cardiac disease on a slice of material no larger than a credit card.

In a revolutionary new approach, University of Miami researchers are combining traditional engineering structures and materials, like metal or plastic, with stem cells from rodents and humans to create organs on a chip—simulated organs that mimic how human organs function, both normally and when diseased.

By recreating functional models of human physiology and pathophysiology, researchers from the University’s College of Engineering and Miller School of Medicine, along with industry partners, are testing novel therapies and uncovering the biological mechanisms of human disease.

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